{"id":266,"date":"2025-11-23T09:09:38","date_gmt":"2025-11-23T08:09:38","guid":{"rendered":"https:\/\/doctor-to-be.org\/forschung\/"},"modified":"2026-06-04T15:54:38","modified_gmt":"2026-06-04T14:54:38","slug":"forschung","status":"publish","type":"page","link":"https:\/\/doctor-to-be.org\/de\/forschung\/","title":{"rendered":"Forschung"},"content":{"rendered":"<section class=\"bde-section-266-100 bde-section\">\n  \n  \n\t\n\n\n\n<div class=\"section-container\"><h1 class=\"bde-heading-266-101 bde-heading\">\nForschung\n<\/h1><\/div>\n<\/section><section class=\"bde-section-266-102 bde-section\">\n  \n  \n\t\n\n\n\n<div class=\"section-container\"><h2 class=\"bde-heading-266-103 bde-heading\">\nErhebung der Wirkungen eines konditionierten Open-Label-Placebos mit dem Ziel, eine m\u00f6gliche Reduzierung der symptomatischen medikament\u00f6sen Behandlung unter \u00e4rztlicher Begleitung zu untersuchen oder ihre Wirkung zu verst\u00e4rken.\n<\/h2><div class=\"bde-rich-text-266-104 bde-rich-text breakdance-rich-text-styles\">\n<p>Forschung in den Bereichen Behandlung chronischer Schmerzen, symptomatische Behandlung allergischer Beschwerden, Verst\u00e4rkung der Wirkung einer Chemotherapie, Unterst\u00fctzung der Rauchentw\u00f6hnung, Koffein ersetzen, Reduzierung von Depressionen und Panikattacken sowie Unterst\u00fctzung der Gewichtsabnahme usw. \u2026<\/p>\n<\/div><\/div>\n<\/section><section class=\"bde-section-266-105 bde-section\">\n  \n  \n\t\n\n\n\n<div class=\"section-container\"><div class=\"bde-columns-266-106 bde-columns\"><div class=\"bde-column-266-107 bde-column\">\n  \n  \n\t\n\n\n\n<div class=\"bde-div-266-108 bde-div\">\n  \n  \n\t\n\n\n\n<h3 class=\"bde-heading-266-109 bde-heading\">\nErfahrungen anderer\n<\/h3><div class=\"bde-rich-text-266-110 bde-rich-text breakdance-rich-text-styles\">\n<p>Hier werden die Erfahrungen derjenigen gesammelt, die sie gerne mit uns teilen. M\u00f6chtest du es auch ausprobieren? Oder hast du bereits eine Erfahrung damit, die du teilen kannst? Bitte f\u00fclle <a href=\"https:\/\/forms.gle\/ocoFRRdjWLFUS3aZ7\">diesen Fragebogen<\/a> aus.<\/p>\n<p>Meine ersten Versuche, die Methode mit anderen zu teilen, f\u00fchrten sofort zu interessanten Ergebnissen, sogar zu zweien. Bekannte von mir berichteten dasselbe: Nachdem ich ihnen meine Geschichte erz\u00e4hlt hatte und wir uns mit der Idee verabschiedeten, dass sie die Methode ausprobieren w\u00fcrden, folgte keiner von ihnen dem Weg, den ich gegangen war. Statt zu Hause mit der Konditionierung zu beginnen, h\u00f6rten sie einfach auf, die symptomatischen Medikamente anzuwenden, die sie seit Jahren gegen Allergien verwendet hatten, nachdem sie ihre eigene Situation bei Bedarf mit ihrer behandelnden \u00c4rztin oder ihrem behandelnden Arzt besprochen hatten, und nach meinen letzten Informationen brauchen sie sie seitdem nicht mehr und es geht ihnen gut. Eine Person f\u00fcgte noch hinzu, dass sie glaube, alles entscheide sich im Kopf.<\/p>\n<p>Was die Erkl\u00e4rung daf\u00fcr ist, wei\u00df ich vorerst nicht, aber f\u00fcr mich deutet es darauf hin, dass es wahrscheinlich viele gute Wege gibt. Ich hoffe, dass wir bald mehr wissen werden, wenn weitere Erfahrungen eintreffen\u2026<\/p>\n<\/div>\n<\/div><div class=\"bde-div-266-111 bde-div\">\n  \n  \n\t\n\n\n\n<h3 class=\"bde-heading-266-112 bde-heading\">\n\u00c4hnliche Studien\n<\/h3><div class=\"bde-rich-text-266-135 bde-rich-text breakdance-rich-text-styles\">\n<p>Die meisten der unten aufgef\u00fchrten Studien befassen sich mit konditioniertem Placebo; wo dies nicht der Fall ist, habe ich es angegeben. Der Vollst\u00e4ndigkeit halber habe ich auch diejenigen Artikel aufgenommen, in denen mit einem konditionierten Placebo-Setup geforscht wurde, dessen Wirksamkeit jedoch nicht nachgewiesen werden konnte.<\/p>\n<\/div><div class=\"bde-frequently-asked-questions-266-134 bde-frequently-asked-questions\" data-entrance=\"slideDown\" data-parallax=\"false\">\n      <div class=\"bde-faq__item\">\n      <h3 class=\"bde-faq__title-tag\">\n       <button id=\"bde-faq-134-button-1\" aria-expanded=\"false\" aria-controls=\"bde-faq-134-1\" class=\"bde-faq__question js-faq-item\">\n          <span class=\"bde-faq__title\">F\u00e1jdalomcsillap\u00edt\u00e1s<\/span>\n                           <div aria-hidden=\"true\" class=\"bde-faq__icon bde-faq__icon--inactive\">\n                                <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 32 32\">\r\n<path d=\"M31 12h-11v-11c0-0.552-0.448-1-1-1h-6c-0.552 0-1 0.448-1 1v11h-11c-0.552 0-1 0.448-1 1v6c0 0.552 0.448 1 1 1h11v11c0 0.552 0.448 1 1 1h6c0.552 0 1-0.448 1-1v-11h11c0.552 0 1-0.448 1-1v-6c0-0.552-0.448-1-1-1z\"\/>\r\n<\/svg>\n                            <\/div>\n         \t  <div aria-hidden=\"true\" class=\"bde-faq__icon bde-faq__icon--active\">\n                                <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\"><!-- Font Awesome Free 5.15.1 by @fontawesome - https:\/\/fontawesome.com License - https:\/\/fontawesome.com\/license\/free (Icons: CC BY 4.0, Fonts: SIL OFL 1.1, Code: MIT License) --><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"\/><\/svg>\n                            <\/div>\n                  <\/button>\n      <\/h3>\n      <div role=\"region\" aria-labelledby=\"bde-faq-134-button-1\" id=\"bde-faq-134-1\" class=\"bde-faq__answer\">\n        <div class=\"bde-faq__answer-content\">\n            <div class=\"breakdance-rich-text-styles\"><p>Kr\u00f3nikusan visszat\u00e9r\u0151 f\u00e1jdalom csillap\u00edt\u00e1s\u00e1ra sikeresen alkalmazt\u00e1k a kondicion\u00e1l\u00e1s technik\u00e1j\u00e1t.<\/p>\n<p>Els\u0151 esetben egy <strong>baleset ut\u00e1ni oxycodon ter\u00e1pi\u00e1ban tudt\u00e1k null\u00e1ra cs\u00f6kkenteni a d\u00f3zist<\/strong>. <a href=\"\\&quot;https:\/\/www.frontiersin.org\/journals\/pain-research\/articles\/10.3389\/fpain.2021.697475\/full\\&quot;\" target=\"\\&quot;_blank\\&quot;\" rel=\"\\&quot;noopener\\&quot;\">\u2028Estudillo-Guerra MA, Mesia-Toledo I, Schneider JC and Morales-Quezada L (2021) The Use of Conditioning Open-Label Placebo in Opioid Dose Reduction: A Case Report and Literature Review. Front. Pain Res. 2:697475. doi: 10.3389\/fpain.2021.697475<\/a><\/p>\n<p>M\u00e1sodik esetben <strong>gerincm\u0171t\u00e9t ut\u00e1ni f\u00e1jdalomcsillap\u00edt\u00e1sban haszn\u00e1lt\u00e1k a kondicion\u00e1lt open-label placebo technik\u00e1t<\/strong> 51 kiv\u00e1lasztott betegen. B\u00e1r a meg\u00e9lt napi \u00e1tlagos f\u00e1jdalomszintben nem mutatkozott jelent\u0151s k\u00fcl\u00f6nbs\u00e9g,\u00a0 szignifik\u00e1ns k\u00fcl\u00f6nbs\u00e9get tudtak kimutatni a betegek napi maxim\u00e1lis f\u00e1jdalom\u00e9rt\u00e9k\u00e9ben, valamint a COLP csoport \u00e1tlagos morfin milligramm ekvivalens fogyaszt\u00e1sa ca. 30%-kal volt kevesebb.\u2028 <a href=\"\\&quot;https:\/\/pubmed.ncbi.nlm.nih.gov\/33449503\/\\&quot;\" target=\"\\&quot;_blank\\&quot;\" rel=\"\\&quot;noopener\\&quot;\">Flowers KM, Patton ME, Hruschak VJ, Fields KG, Schwartz E, Zeballos J, et al. . Conditioned open-label placebo for opioid reduction after spine surgery: a randomized controlled trial. Pain. (2021) 162:1828\u201339. doi: 10.1097\/j.pain.0000000000002185\u00a0\u2013\u00a0DOI\u00a0\u2013\u00a0PMC\u00a0\u2013\u00a0PubMed<\/a><\/p>\n<p><strong>K\u00f3rh\u00e1zban fekv\u0151 betegek opioid ig\u00e9ny<\/strong>\u00e9t \u00e9s f\u00e1jdalm\u00e1t is szignifik\u00e1ns m\u00e9rt\u00e9kben tudt\u00e1k cs\u00f6kkenteni.\u2028 <a href=\"\\&quot;https:\/\/journals.lww.com\/painrpts\/fulltext\/2020\/08000\/conditioning_open_label_placebo__a_pilot.3.aspx\\&quot;\" target=\"\\&quot;_blank\\&quot;\" rel=\"\\&quot;noopener\\&quot;\">Morales-Quezada, Leona,*; Mesia-Toledo, Inesa; Estudillo-Guerra, Anayalia; O\u2019Connor, Kevin C.a; Schneider, Jeffrey C.a; Sohn, Douglas J.a; Crandell, David M.a; Kaptchuk, Tedb; Zafonte, Rossa. Conditioning open-label placebo: a pilot pharmacobehavioral approach for opioid dose reduction and pain control. PAIN Reports 5(4):p e828, July\/August 2020. | DOI: 10.1097\/PR9.0000000000000828<\/a><\/p>\n<p>Egy m\u00e1sik kutat\u00e1s <strong>opioid f\u00e1jdalomcsillap\u00edt\u00e1sr\u00f3l<\/strong><\/p>\n<p><a href=\"https:\/\/journals.lww.com\/painrpts\/fulltext\/2020\/08000\/conditioning_open_label_placebo__a_pilot.3.aspx\">Morales-Quezada, Leona,*; Mesia-Toledo, Inesa; Estudillo-Guerra, Anayalia; O'Connor, Kevin C.a; Schneider, Jeffrey C.a; Sohn, Douglas J.a; Crandell, David M.a; Kaptchuk, Tedb; Zafonte, Rossa. Conditioning open-label placebo: a pilot pharmacobehavioral approach for opioid dose reduction and pain control. PAIN Reports 5(4):p e828, July\/August 2020. | DOI: 10.1097\/PR9.0000000000000828 <\/a><\/p>\n<div class=\"highwire-citation-info\">\n<div id=\"citation-node-356113--228165903\" class=\"highwire-article-citation highwire-citation-type-highwire-article cite-tool-node356113\" data-node-nid=\"356113\" data-pisa=\"jneuro;19\/1\/484\" data-pisa-master=\"jneuro;19\/1\/484\" data-apath=\"\/jneuro\/19\/1\/484.atom\">\n<div class=\"highwire-cite highwire-cite-highwire-article highwire-citation-jnl-eneuro-styles-jcore-standard-plus clearfix\">\n<div>\n<div>\n<div class=\"flex flex-col gap-1.5 relative pt-2 [&amp;:not(:last-child)]:border-b border-border\" data-testid=\"note-item\">\n<div class=\"flex gap-1.5\">\n<div class=\"w-full flex flex-col gap-1.5\">\n<div class=\"p-2 pb-1 border border-transparent rounded-default !mb-1.5\">\n<div class=\"\">\n<div class=\"prose prose-hr:mb-5 prose-h2:!text-lg prose-h2:text-main-text font-normal [&amp;_*]:font-normal [&amp;_hr]:border-background [&amp;_p]:text-current space-y-0 prose-ol:my-0 prose-li:my-0.5 prose-p:my-0 prose-headings:my-1.5 prose-a:!text-primary-200 prose-a:!no-underline hover:prose-a:!underline text-detailsText !text-2xs !prose-sm mb-1 [&amp;_*]:text-main-text\">\n<p><strong>Bonyolult k\u00eds\u00e9rlet Morfin, Ketorolac \u00e9s Naloxen<\/strong> valamint s\u00f3oldat kombin\u00e1l\u00e1s\u00e1val. A placebo \u00e1ltal kiv\u00e1ltott f\u00e1jdalomcsillap\u00edt\u00e1st is k\u00f6z\u00f6mb\u00f6s\u00edteni tudt\u00e1k Naloxennel (opioid t\u00faladagol\u00e1sban haszn\u00e1lt gy\u00f3gyszer). Ez azt bizony\u00edtja hogy a placebo f\u00e1jdalomcsillap\u00edt\u00e1s bels\u0151 opioidokat szabad\u00edtott fel, amelyek hat\u00e1s\u00e1t az opioid receptorokat blokkol\u00f3 Naloxen k\u00f6z\u00f6mb\u00f6s\u00edteni tudott.<\/p>\n<p><a href=\"https:\/\/www.jneurosci.org\/content\/19\/1\/484\">Neuropharmacological Dissection of Placebo Analgesia: Expectation-Activated Opioid Systems versus Conditioning-Activated Specific Subsystems<\/a>, <a href=\"https:\/\/www.jneurosci.org\/content\/19\/1\/484\"><span class=\"highwire-citation-authors\"><span class=\"highwire-citation-author first\" data-delta=\"0\">Martina Amanzio<\/span>, <span class=\"highwire-citation-author\" data-delta=\"1\">Fabrizio Benedetti, <\/span><\/span><\/a><a href=\"https:\/\/www.jneurosci.org\/content\/19\/1\/484\"><span class=\"highwire-cite-metadata-journal highwire-cite-metadata\">Journal of Neuroscience <\/span><span class=\"highwire-cite-metadata-date highwire-cite-metadata\">1 January 1999, <\/span><span class=\"highwire-cite-metadata-volume highwire-cite-metadata\">19 <\/span><span class=\"highwire-cite-metadata-issue highwire-cite-metadata\">(1) <\/span><span class=\"highwire-cite-metadata-pages highwire-cite-metadata\">484-494; <\/span><span class=\"highwire-cite-metadata-doi highwire-cite-metadata\"><span class=\"label\">DOI:<\/span> 10.1523\/JNEUROSCI.19-01-00484.1999<\/span><\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p>\u00a0<\/p><\/div>\n\n                    <\/div>\n      <\/div>\n    <\/div>\n      <div class=\"bde-faq__item\">\n      <h3 class=\"bde-faq__title-tag\">\n       <button id=\"bde-faq-134-button-2\" aria-expanded=\"false\" aria-controls=\"bde-faq-134-2\" class=\"bde-faq__question js-faq-item\">\n          <span class=\"bde-faq__title\">Szerhaszn\u00e1lat (opioid, koffein)<\/span>\n                           <div aria-hidden=\"true\" class=\"bde-faq__icon bde-faq__icon--inactive\">\n                                <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 32 32\">\r\n<path d=\"M31 12h-11v-11c0-0.552-0.448-1-1-1h-6c-0.552 0-1 0.448-1 1v11h-11c-0.552 0-1 0.448-1 1v6c0 0.552 0.448 1 1 1h11v11c0 0.552 0.448 1 1 1h6c0.552 0 1-0.448 1-1v-11h11c0.552 0 1-0.448 1-1v-6c0-0.552-0.448-1-1-1z\"\/>\r\n<\/svg>\n                            <\/div>\n         \t  <div aria-hidden=\"true\" class=\"bde-faq__icon bde-faq__icon--active\">\n                                <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\"><!-- Font Awesome Free 5.15.1 by @fontawesome - https:\/\/fontawesome.com License - https:\/\/fontawesome.com\/license\/free (Icons: CC BY 4.0, Fonts: SIL OFL 1.1, Code: MIT License) --><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"\/><\/svg>\n                            <\/div>\n                  <\/button>\n      <\/h3>\n      <div role=\"region\" aria-labelledby=\"bde-faq-134-button-2\" id=\"bde-faq-134-2\" class=\"bde-faq__answer\">\n        <div class=\"bde-faq__answer-content\">\n            <div class=\"breakdance-rich-text-styles\"><p><strong>Opioid use disorder kezel\u00e9s\u00e9ben<\/strong> 131 p\u00e1cienst vizsg\u00e1ltak COLP m\u00f3dszerrel. B\u00e1r az eredm\u00e9ny nem cs\u00f6kkentette jelent\u0151sen a bevitt Methadone mennyis\u00e9g\u00e9t, viszont szignifik\u00e1ns eredm\u00e9nyt lehetett kimutatni a 90-napos programban marad\u00e1si eredm\u00e9nyekben \u00e9s az alv\u00e1smin\u0151s\u00e9g javul\u00e1s\u00e1ban.\u2028 <a href=\"\\&quot;https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/fullarticle\/2803739\\&quot;\" target=\"\\&quot;_blank\\&quot;\" rel=\"\\&quot;noopener\\&quot;\">Belcher AM, Cole TO, Massey E, et al. Effectiveness of Conditioned Open-label Placebo With Methadone in Treatment of Opioid Use Disorder: A Randomized Clinical Trial.\u00a0JAMA Netw Open.\u00a02023;6(4):e237099. doi:10.1001\/jamanetworkopen.2023.7099<\/a><\/p>\n<p><strong>Koffein \u00e9s kondicion\u00e1lt placebo.<\/strong> K\u00e1v\u00e9iv\u00e1sban edzett (=kondicion\u00e1lt) egy\u00e9nekkel itattak koffeinmentes k\u00e1v\u00e9t, koffeintartalm\u00fa narancslevet \u00e9s semleges italt. A koffein \u00e9s a koffeinmentes k\u00e1v\u00e9 egyform\u00e1n jav\u00edtotta a szubjekt\u00edv \u00e9s m\u00e9rhet\u0151 \u00e9bers\u00e9get. A kondicion\u00e1lt stimulus itt a k\u00e1v\u00e9iv\u00e1s maga (a szertart\u00e1s, illat ...).<\/p>\n<p><a href=\"https:\/\/link.springer.com\/article\/10.1007\/s002130051038\">Flaten, M., Blumenthal, T. Caffeine-associated stimuli elicit conditioned responses: an experimental model of the placebo effect. <i>Psychopharmacology<\/i> <b>145<\/b>, 105\u2013112 (1999). https:\/\/doi.org\/10.1007\/s002130051038<\/a><\/p>\n<p>\u00a0<\/p>\n<p>Egy \u00fajabb k\u00eds\u00e9rlet: a<strong> koffeinmentes k\u00e1v\u00e9<\/strong> is javitja a reakcioid\u0151t \u00e1lmos emberekben.<\/p>\n<p><a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/hup.931?casa_token=z7Gtn-JDtyUAAAAA%3AKRxJ9x7duRnSDzQAKbfJ7NZlChH-b_CAMsCXU0k5ZSlmBzOnFyU9iM-X_BS43swixrk1F8fY5kQuAek\">Anderson, C. and Horne, J.A. (2008), Placebo response to caffeine improves reaction time performance in sleepy people. Hum. Psychopharmacol. Clin. Exp., 23: 333-336. https:\/\/doi.org\/10.1002\/hup.931<\/a><\/p><\/div>\n\n                    <\/div>\n      <\/div>\n    <\/div>\n      <div class=\"bde-faq__item\">\n      <h3 class=\"bde-faq__title-tag\">\n       <button id=\"bde-faq-134-button-3\" aria-expanded=\"false\" aria-controls=\"bde-faq-134-3\" class=\"bde-faq__question js-faq-item\">\n          <span class=\"bde-faq__title\">Allergia<\/span>\n                           <div aria-hidden=\"true\" class=\"bde-faq__icon bde-faq__icon--inactive\">\n                                <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 32 32\">\r\n<path d=\"M31 12h-11v-11c0-0.552-0.448-1-1-1h-6c-0.552 0-1 0.448-1 1v11h-11c-0.552 0-1 0.448-1 1v6c0 0.552 0.448 1 1 1h11v11c0 0.552 0.448 1 1 1h6c0.552 0 1-0.448 1-1v-11h11c0.552 0 1-0.448 1-1v-6c0-0.552-0.448-1-1-1z\"\/>\r\n<\/svg>\n                            <\/div>\n         \t  <div aria-hidden=\"true\" class=\"bde-faq__icon bde-faq__icon--active\">\n                                <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\"><!-- Font Awesome Free 5.15.1 by @fontawesome - https:\/\/fontawesome.com License - https:\/\/fontawesome.com\/license\/free (Icons: CC BY 4.0, Fonts: SIL OFL 1.1, Code: MIT License) --><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"\/><\/svg>\n                            <\/div>\n                  <\/button>\n      <\/h3>\n      <div role=\"region\" aria-labelledby=\"bde-faq-134-button-3\" id=\"bde-faq-134-3\" class=\"bde-faq__answer\">\n        <div class=\"bde-faq__answer-content\">\n            <div class=\"breakdance-rich-text-styles\"><p><strong>H\u00e1ziporatka allergia.<\/strong> A kondicion\u00e1l\u00e1s desloratadin gy\u00f3gyszer+ sz\u00f6rppel, illetve hat\u00f3anyagmentes tabletta+ sz\u00f6rppel t\u00f6rt\u00e9nt. Az el\u0151h\u00edv\u00e1si f\u00e1zisban mindk\u00e9t csoport (teh\u00e1t azok is akik nem tal\u00e1lkoztak a hat\u00f3anyaggal) j\u00f3l telje\u00edtett. Akik gy\u00f3gyszert is kaptak a tanul\u00e1si szakaszban azok jobb eredm\u00e9nnyel teljes\u00edtettek. Ez azt mutatja, hogy az elv\u00e1r\u00e1soknak is jelent\u0151s hat\u00e1sa lehet.<\/p>\n<p><a title=\"Back to original article\" href=\"https:\/\/doi.org\/10.1371\/journal.pone.0079576\">\u00a0<strong>Cognitive Factors Mediate Placebo Responses in Patients with House Dust Mite Allergy<\/strong> <\/a> <br \/><a href=\"https:\/\/doi.org\/10.1371\/journal.pone.0079576\">Vits\u00a0S, Cesko\u00a0E, Benson\u00a0S, Rueckert\u00a0A, Hillen\u00a0U, et al. (2013) Cognitive Factors Mediate Placebo Responses in Patients with House Dust Mite Allergy. PLOS ONE 8(11): e79576.<\/a> <a href=\"https:\/\/doi.org\/10.1371\/journal.pone.0079576\">https:\/\/doi.org\/10.1371\/journal.pone.0079576<\/a><\/p>\n<p>\u00a0<\/p>\n<p><strong>Eg\u00e9szs\u00e9ges emberekben hisztamin iontofor\u00e9zissel keltettek viszket\u00e9st<\/strong>, ennek m\u00e9rt\u00e9k\u00e9t vizsg\u00e1lt\u00e1k el\u0151z\u0151leg antihisztaminra kondicion\u00e1lt csoportokban (open \u00e9s closed label) . Csup\u00e1n alacsony k\u00fcl\u00f6nbs\u00e9get siker\u00fclt kimutatni a csoportok k\u00f6z\u00f6tt a placebo jav\u00e1ra.\u2028 <a href=\"\\&quot;https:\/\/pubmed.ncbi.nlm.nih.gov\/31490841\/\\&quot;\" target=\"\\&quot;_blank\\&quot;\" rel=\"\\&quot;noopener\\&quot;\">Meeuwis SH, van Middendorp H, Pacheco-Lopez G, Ninaber MK, Lavrijsen APM, van der Wee N, Veldhuijzen DS, Evers AWM. Antipruritic Placebo Effects by Conditioning H1-antihistamine. Psychosom Med. 2019 Nov\/Dec;81(9):841-850. doi: 10.1097\/PSY.0000000000000743. PMID: 31490841; PMCID: PMC6844655<\/a>.<\/p>\n<p>\u00a0<\/p>\n<p><strong>Antihisztamin tablett\u00e1t kondicion\u00e1ltak sz\u00f6rppel<\/strong>, kisebb hat\u00e1ssal ugyan, mint az antihisztamin de a placebo is cs\u00f6kkentette a Prick teszten m\u00e9rhet\u0151 allergi\u00e1s t\u00fcneteket.<\/p>\n<p><a href=\"https:\/\/karger.com\/nim\/article\/33\/1\/75\/944480\/Experimental-Approach-to-Inducing-Anti\">Stefanie H\u00f6lsken<span class=\"al-author-delim\">, <\/span>Eva Holubek<span class=\"al-author-delim\">, <\/span>Frederik Krefting<span class=\"al-author-delim\">, <\/span>Senta M\u00fchlhaus<span class=\"al-author-delim\">, <\/span>Daniela Bese<span class=\"al-author-delim\">, <\/span>Joachim Dissemond<span class=\"al-author-delim\">, <\/span>Oliver Pfaar<span class=\"al-author-delim\">, <\/span>Winfried Rief<span class=\"al-author-delim\">, <\/span>Manfred Schedlowski<span class=\"al-author-delim\">, <\/span>Wiebke Sondermann; Experimental Approach to Inducing Anti-Histaminergic Placebo Effects: A Randomized Controlled Trial in Healthy Volunteers. <em>Neuroimmunomodulation<\/em> 1 January 2026; 33 (1): 75\u201388.<\/a> <a href=\"https:\/\/doi.org\/10.1159\/000549975\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.1159\/000549975<\/a><\/p>\n<p>\u00a0<\/p><\/div>\n\n                    <\/div>\n      <\/div>\n    <\/div>\n      <div class=\"bde-faq__item\">\n      <h3 class=\"bde-faq__title-tag\">\n       <button id=\"bde-faq-134-button-4\" aria-expanded=\"false\" aria-controls=\"bde-faq-134-4\" class=\"bde-faq__question js-faq-item\">\n          <span class=\"bde-faq__title\">Immunrendszerre hat\u00f3 szerek (transzplant\u00e1ci\u00f3, daganatok)<\/span>\n                           <div aria-hidden=\"true\" class=\"bde-faq__icon bde-faq__icon--inactive\">\n                                <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 32 32\">\r\n<path d=\"M31 12h-11v-11c0-0.552-0.448-1-1-1h-6c-0.552 0-1 0.448-1 1v11h-11c-0.552 0-1 0.448-1 1v6c0 0.552 0.448 1 1 1h11v11c0 0.552 0.448 1 1 1h6c0.552 0 1-0.448 1-1v-11h11c0.552 0 1-0.448 1-1v-6c0-0.552-0.448-1-1-1z\"\/>\r\n<\/svg>\n                            <\/div>\n         \t  <div aria-hidden=\"true\" class=\"bde-faq__icon bde-faq__icon--active\">\n                                <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\"><!-- Font Awesome Free 5.15.1 by @fontawesome - https:\/\/fontawesome.com License - https:\/\/fontawesome.com\/license\/free (Icons: CC BY 4.0, Fonts: SIL OFL 1.1, Code: MIT License) --><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"\/><\/svg>\n                            <\/div>\n                  <\/button>\n      <\/h3>\n      <div role=\"region\" aria-labelledby=\"bde-faq-134-button-4\" id=\"bde-faq-134-4\" class=\"bde-faq__answer\">\n        <div class=\"bde-faq__answer-content\">\n            <div class=\"breakdance-rich-text-styles\"><p><strong>Szervtranszplant\u00e1ci\u00f3n<\/strong> \u00e1tesett betegeknek folyamatosan el kell nyomni az immunrendszer\u00e9t, hogy az idegen szerv kil\u00f6k\u0151d\u00e9s\u00e9t megel\u0151zz\u00fck. Ezen szerek mell\u00e9khat\u00e1sai is sajnos megjelennek a kezel\u00e9s sor\u00e1n. Ebben a kis\u00e9rletben az immunszupressziv szert kondicion\u00e1lt\u00e1k egy speci\u00e1lis \u00edzhez. Jelent\u0151s T sejtsz\u00e1m k\u00fcl\u00f6nbs\u00e9get cs\u00f6kken\u00e9st lehetett m\u00e9rni a placebo bead\u00e1sa el\u0151tt \u00e9s ut\u00e1ni id\u0151pontokban.<\/p>\n<p><a href=\"https:\/\/www.pnas.org\/doi\/abs\/10.1073\/pnas.1720548115\">J. Kirchhof, L. Petrakova, A. Brinkhoff, S. Benson, J. Schmidt, M. Unteroberd\u00f6rster, B. Wilde, T.J. Kaptchuk, O. Witzke, &amp; M. Schedlowski, Learned immunosuppressive placebo responses in renal transplant patients, Proc. Natl. Acad. Sci. U.S.A. 115 (16) 4223-4227, https:\/\/doi.org\/10.1073\/pnas.1720548115 (2018).<\/a><\/p>\n<p>\u00a0<\/p>\n<p>Hasonl\u00f3an az el\u0151z\u0151 k\u00eds\u00e9rlethez itt is<strong> immunszupressz\u00e1ns<\/strong>t kondicion\u00e1ltak. Azt vett\u00e9k \u00e9szre hogy 14 olyan alkalom ut\u00e1n amikor a p\u00e1ciens csak placebot kapott a hat\u00e1s megsz\u0171nt. Azonban ha id\u0151nk\u00e9nt alacsony d\u00f3zisban ism\u00e9t adtak gy\u00f3gyszert a placebo mell\u00e9, akkor <strong>a hat\u00e1s hossz\u00fa t\u00e1von is megmaradt<\/strong>.<\/p>\n<p><a href=\"https:\/\/ascpt.onlinelibrary.wiley.com\/doi\/full\/10.1038\/clpt.2014.75\">Albring, A., Wendt, L., Benson, S., Nissen, S., Yavuz, Z., Engler, H., Witzke, O. and Schedlowski, M. (2014), Preserving Learned Immunosuppressive Placebo Response: Perspectives for Clinical Application. Clinical Pharmacology &amp; Therapeutics, 96: 247-255. https:\/\/doi.org\/10.1038\/clpt.2014.75<\/a><\/p>\n<p>\u00a0<\/p>\n<p>Kondicion\u00e1lt immunszupresszi\u00f3: m\u00e1r <strong>4 alkalom is tart\u00f3s kapcsolatot alak\u00edtott ki<\/strong>, 1 alkalmas kapcsol\u00e1s j\u00f3val alacsonyabb hat\u00e1ssal b\u00edrt. Ha nem volt kapcsol\u00e1s, csak elv\u00e1r\u00e1s, az nem hozta meg a m\u00e9rhet\u0151 eredm\u00e9nyt.<\/p>\n<p><a title=\"Back to original article\" href=\"https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0049477\">\u00a0<strong>Placebo Effects on the Immune Response in Humans: The Role of Learning and Expectation<\/strong> <\/a> <br \/><a href=\"https:\/\/doi.org\/10.1371\/journal.pone.0049477\">Albring\u00a0A, Wendt\u00a0L, Benson\u00a0S, Witzke\u00a0O, Kribben\u00a0A, et al. (2012) Placebo Effects on the Immune Response in Humans: The Role of Learning and Expectation. PLOS ONE 7(11): e49477.<\/a> <a href=\"https:\/\/doi.org\/10.1371\/journal.pone.0049477\">https:\/\/doi.org\/10.1371\/journal.pone.0049477<\/a><\/p>\n<p>\u00a0<\/p>\n<p><strong>Rekombin\u00e1ns hum\u00e1n interferon gamma<\/strong>-t kapcsoltak sz\u00e1jon kereszt\u00fcl beadott propylen glykollal eg\u00e9szs\u00e9ges emberekben. A propylen glikol \u00f6nmag\u00e1ban is ki tudta v\u00e1ltani a v\u00e1laszt.\u00a0<\/p>\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S152166169894637X?via%3Dihub\">D.L. Longo, P.L. Duffey, W.C. Kopp, M.P. Heyes, W.G. Alvord, W.H. Sharfman, P.J. Schmidt, D.R. Rubinow, D.L. Rosenstein,\u00a0<\/a><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S152166169894637X?via%3Dihub\">Conditioned Immune Response to Interferon-\u03b3 in Humans, Clinical Immunology, Volume 90, Issue 2, 1999, Pages 173-181, ISSN 1521-6616, https:\/\/doi.org\/10.1006\/clim.1998.4637.<\/a><\/p>\n<p>\u00a0<\/p>\n<p><strong>Cyclosporin A<\/strong>-t kondicion\u00e1ltak k\u00fcl\u00f6nleges \u00edz\u0171 itallal. Az el\u0151h\u00edv\u00e1si szakaszban csup\u00e1n az ital okozott jelent\u0151s, m\u00e9rhet\u0151 IL-2 \u00e9s IFN gamma szint cs\u00f6kekn\u00e9st, hasonl\u00f3 hat\u00e1st \u00e9rve el ezzel, mint a gy\u00f3gyszerhat\u00e1s. Ez volt az els\u0151 alkalom amikor immunszupresszi\u00f3 kondicion\u00e1l\u00e1s hat\u00e1soss\u00e1g\u00e1t bizony\u00edtott\u00e1k.<\/p>\n<p><a href=\"https:\/\/faseb.onlinelibrary.wiley.com\/doi\/10.1096\/fj.02-0389com\">Goebel, M.U., Trebst, A.E., Steiner, J., Xie, Y.F., Exton, M.S., Frede, S., Canbay, A.E., Michel, M.C., Heemann, U. and Schedlowski, M. (2002), Behavioral conditioning of immunosuppression is possible in humans. The FASEB Journal, 16: 1869-1873. https:\/\/doi.org\/10.1096\/fj.02-0389com<\/a><\/p>\n<p>\u00a0<\/p>\n<p>Szint\u00e9n <strong>Cycosporin A<\/strong>-t kondicionaltak egyedi \u00edzzel <strong>patk\u00e1nyokban \u00e9s emberekben is<\/strong>. Ahogy az el\u0151z\u0151 k\u00eds\u00e9rletben is t\u00f6rt\u00e9nt, m\u00e9rhet\u0151 cs\u00f6kken\u00e9st tudtak kimutatni az IL-2 \u00e9sIFN gamma szintekben csak az ital fogyaszt\u00e1sa ut\u00e1n. Emberekben 11, patk\u00e1nyokban 6 nappal <strong>k\u00e9s\u0151bb, ism\u00e9t siker\u00fclt<\/strong> csup\u00e1n a placeboval jelent\u0151s hat\u00e1st el\u00e9rni, ism\u00e9telt gy\u00f3gyszeradagol\u00e1s n\u00e9lk\u00fcl.<\/p>\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0889159111001905?via%3Dihub\">Timo Wirth, Kirstin Ober, Geraldine Prager, Magdalene Vogelsang, Sven Benson, Oliver Witzke, Andreas Kribben, Harald Engler, Manfred Schedlowski, Repeated recall of learned immunosuppression: Evidence from rats and men, Brain, Behavior, and Immunity, Volume 25, Issue 7, 2011, Pages 1444-1451, ISSN 0889-1591,<\/a><br \/><a href=\"https:\/\/doi.org\/10.1016\/j.bbi.2011.05.011.\">https:\/\/doi.org\/10.1016\/j.bbi.2011.05.011.<\/a><\/p>\n<p>\u00a0<\/p>\n<p><strong>Eml\u0151daganat kezel\u00e9s\u00e9t<\/strong> - a beteg tudt\u00e1val - kieg\u00e9sz\u00edtett\u00e9k hat\u00f3anyag n\u00e9lk\u00fcli fiziol\u00f3gi\u00e1s s\u00f3oldat inf\u00fazi\u00f3val. A kondicion\u00e1l\u00e1s itt a kemoter\u00e1pi\u00e1s szer \u00e9s az infuzi\u00f3 k\u00f6z\u00f6tt j\u00f6tt l\u00e9tre. A daganatot puszt\u00edt\u00f3 immunsejtek sz\u00e1m\u00e1nak n\u00f6veked\u00e9se a v\u00e9rmint\u00e1kban m\u00e9rhet\u0151 volt. Szerintem ez \u00f3ri\u00e1si \u00f6tlet!<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21607425\/\">Lekander M, Furst C, Rotstein S, Blomgren H, Fredrikson M. Does informed adjuvant placebo chemotherapy for breast-cancer elicit immune changes. Oncol Rep. 1994 Jul;1(4):699-703. doi: 10.3892\/or.1.4.699. PMID: 21607425.<\/a><\/p>\n<p>\u00a0<\/p>\n<p><strong>A fej \u00e9s nyakdaganatos p\u00e1ciensek<\/strong> f\u00e1jdalomcsillap\u00edt\u00e1s\u00e1val kapcsolatban is folyik tanulm\u00e1ny.\u2028<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37419646\/\">Trakimas DR, Colloca L, Fakhry C, et al Study protocol: randomised controlled trial of conditioned open-label placebo (COLP) for perioperative pain management in patients with head and neck cancerBMJ Open 2023;13:e069785. doi: 10.1136\/bmjopen-2022-069785<\/a><\/p>\n<p>\u00a0<\/p><\/div>\n\n                    <\/div>\n      <\/div>\n    <\/div>\n      <div class=\"bde-faq__item\">\n      <h3 class=\"bde-faq__title-tag\">\n       <button id=\"bde-faq-134-button-5\" aria-expanded=\"false\" aria-controls=\"bde-faq-134-5\" class=\"bde-faq__question js-faq-item\">\n          <span class=\"bde-faq__title\">Fogy\u00f3k\u00fara, obesitas, cukorbetegs\u00e9g<\/span>\n                           <div aria-hidden=\"true\" class=\"bde-faq__icon bde-faq__icon--inactive\">\n                                <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 32 32\">\r\n<path d=\"M31 12h-11v-11c0-0.552-0.448-1-1-1h-6c-0.552 0-1 0.448-1 1v11h-11c-0.552 0-1 0.448-1 1v6c0 0.552 0.448 1 1 1h11v11c0 0.552 0.448 1 1 1h6c0.552 0 1-0.448 1-1v-11h11c0.552 0 1-0.448 1-1v-6c0-0.552-0.448-1-1-1z\"\/>\r\n<\/svg>\n                            <\/div>\n         \t  <div aria-hidden=\"true\" class=\"bde-faq__icon bde-faq__icon--active\">\n                                <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\"><!-- Font Awesome Free 5.15.1 by @fontawesome - https:\/\/fontawesome.com License - https:\/\/fontawesome.com\/license\/free (Icons: CC BY 4.0, Fonts: SIL OFL 1.1, Code: MIT License) --><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"\/><\/svg>\n                            <\/div>\n                  <\/button>\n      <\/h3>\n      <div role=\"region\" aria-labelledby=\"bde-faq-134-button-5\" id=\"bde-faq-134-5\" class=\"bde-faq__answer\">\n        <div class=\"bde-faq__answer-content\">\n            <div class=\"breakdance-rich-text-styles\"><p><strong>A Nature cikke arr\u00f3l, hogy hogyan jav\u00edtotta a ny\u00edlt placebo a s\u00falycs\u00f6kken\u00e9st obesit\u00e1s kezel\u00e9s\u00e9ben.<\/strong> Ebben a kutat\u00e1sban egy ter\u00e1pia mell\u00e9 adtak egy placebo tablett\u00e1t is az egyik csoportnak. Nem volt olyan szakasz amikor csak a tabletta beszed\u00e9s\u00e9nek hat\u00e1s\u00e1t vizsg\u00e1lt\u00e1k\u00a0 volna, teh\u00e1t nem kifejezetten kondicion\u00e1lt placebor\u00f3l besz\u00e9l\u00fcnk. A nyiltan adott hat\u00f3anyagmentes tablett\u00e1t szed\u0151k azonban jobb fogy\u00e1si eredm\u00e9nyeket tudtak el\u00e9rni.<\/p>\n<p><a href=\"\\&quot;https:\/\/www.nature.com\/articles\/s41598-024-69866-7\\&quot;\" target=\"\\&quot;_blank\\&quot;\" rel=\"\\&quot;noopener\\&quot;\">Schaefer, M., K\u00fchnel, A. &amp; Enge, S. Open-label placebos reduce weight in obesity: a randomized controlled trial.\u00a0Sci Rep\u00a014, 21311 (2024). https:\/\/doi.org\/10.1038\/s41598-024-69866-7<\/a><\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p><\/div>\n\n                    <\/div>\n      <\/div>\n    <\/div>\n      <div class=\"bde-faq__item\">\n      <h3 class=\"bde-faq__title-tag\">\n       <button id=\"bde-faq-134-button-6\" aria-expanded=\"false\" aria-controls=\"bde-faq-134-6\" class=\"bde-faq__question js-faq-item\">\n          <span class=\"bde-faq__title\">Hormon\u00e1lis rendszer<\/span>\n                           <div aria-hidden=\"true\" class=\"bde-faq__icon bde-faq__icon--inactive\">\n                                <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 32 32\">\r\n<path d=\"M31 12h-11v-11c0-0.552-0.448-1-1-1h-6c-0.552 0-1 0.448-1 1v11h-11c-0.552 0-1 0.448-1 1v6c0 0.552 0.448 1 1 1h11v11c0 0.552 0.448 1 1 1h6c0.552 0 1-0.448 1-1v-11h11c0.552 0 1-0.448 1-1v-6c0-0.552-0.448-1-1-1z\"\/>\r\n<\/svg>\n                            <\/div>\n         \t  <div aria-hidden=\"true\" class=\"bde-faq__icon bde-faq__icon--active\">\n                                <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\"><!-- Font Awesome Free 5.15.1 by @fontawesome - https:\/\/fontawesome.com License - https:\/\/fontawesome.com\/license\/free (Icons: CC BY 4.0, Fonts: SIL OFL 1.1, Code: MIT License) --><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"\/><\/svg>\n                            <\/div>\n                  <\/button>\n      <\/h3>\n      <div role=\"region\" aria-labelledby=\"bde-faq-134-button-6\" id=\"bde-faq-134-6\" class=\"bde-faq__answer\">\n        <div class=\"bde-faq__answer-content\">\n            <div class=\"breakdance-rich-text-styles\"><p><strong>Orron kereszt\u00fcl bejuttatott Oxytocin<\/strong>t kondicion\u00e1ltak egy speci\u00e1lis illattal. A kondicion\u00e1l\u00e1s sikeres volt, de hamar elhalv\u00e1nyult. Csak h\u00e1rom napig tartott a kondicion\u00e1l\u00e1s, ahogy az el\u0151h\u00edv\u00e1s is. Tal\u00e1n hosszabb kondicion\u00e1l\u00e1ssal vagy eml\u00e9kezet\u0151 adagokkal jobb eredm\u00e9nyt \u00e9rtek volna el. (l\u00e1sd immunszupressziv k\u00eds\u00e9rletek)<\/p>\n<p><a href=\"https:\/\/journals.lww.com\/bsam\/fulltext\/2020\/01000\/placebo_effects_in_the_neuroendocrine_system_.6.aspx\">Skvortsova, Aleksandrina MSc; Veldhuijzen, Dieuwke S. PhD; Pacheco-Lopez, Gustavo PhD; Bakermans-Kranenburg, Marian PhD; van IJzendoorn, Marinus PhD; Smeets, Monique A.M. PhD; Wilderjans, Tom F. PhD; Dahan, Albert PhD; van den Bergh, Omer PhD; Chavannes, Niels H. PhD; van der Wee, Nic J.A. PhD; Grewen, Karen M. PhD; van Middendorp, Henri\u00ebt PhD; Evers, Andrea W.M. PhD. Placebo Effects in the Neuroendocrine System: Conditioning of the Oxytocin Responses. Psychosomatic Medicine 82(1):p 47-56, January 2020. | DOI: 10.1097\/PSY.0000000000000759<\/a><\/p>\n<p>\u00a0<\/p>\n<p><strong>Orron kereszt\u00fcl bevitt inzulint<\/strong> k\u00f6t\u00f6tt\u00e9k \u00f6ssze r\u00f3zsaolaj illat\u00e1val. A hat\u00e1s nemt\u0151l \u00e9s eg\u00e9szs\u00e9gi \u00e1llapott\u00f3l f\u00fcgg\u00f6tt de j\u00f3l cs\u00f6kkentette az \u00e9hs\u00e9get. A v\u00e9rcukorszint cs\u00f6kkent\u00e9s\u00e9ben kev\u00e9sb\u00e9 volt hat\u00e9kony. <strong>Mindenk\u00e9pp besz\u00e9lj a diabetol\u00f3gusoddal, ha ilyen ir\u00e1nyban t\u00f6r\u00f6d a fejed!<\/strong><\/p>\n<p><a href=\"https:\/\/journals.lww.com\/bsam\/fulltext\/2023\/07000\/influencing_the_insulin_system_by_placebo_effects.12.aspx\">Skvortsova, Aleksandrina PhD; Veldhuijzen, Dieuwke S. PhD; van Dillen, Lotte F. PhD; Zech, Hilmar MSc; Derksen, Suzanne M.J.C. MSc; Sars, Ruben H. MSc; Meijer, Onno C. PhD; Pijl, Hanno PhD; Evers, Andrea W.M. PhD. Influencing the Insulin System by Placebo Effects in Patients With Diabetes Type 2 and Healthy Controls: A Randomized Controlled Trial. Psychosomatic Medicine 85(6):p 551-560, 7\/8 2023. | DOI: 10.1097\/PSY.0000000000001216<\/a><\/p>\n<p>\u00a0<\/p>\n<p>Egy <strong>m\u00e1sik inzulinos k\u00eds\u00e9rlet<\/strong>, orrba juttatva, kondicion\u00e1lva meta-cresol-lal. (sz\u00e1mos inzulink\u00e9sz\u00edtm\u00e9ny tartalmazza mint viv\u0151anyag). Itt is szignifik\u00e1ns eredm\u00e9nyeket tudtak kimutatni. 32 eg\u00e9szs\u00e9ges f\u00e9rfi r\u00e9szv\u00e9tel\u00e9vel.<\/p>\n<p><a href=\"http:\/\/link.springer.com\/article\/10.1007\/s00125-011-2111-y\">Stockhorst, U., de Fries, D., Steingrueber, HJ.\u00a0<i>et al.<\/i>\u00a0Unconditioned and conditioned effects of intranasally administered insulin vs placebo in healthy men: a randomised controlled trial.\u00a0<i>Diabetologia<\/i>\u00a0<b>54<\/b>, 1502\u20131506 (2011). https:\/\/doi.org\/10.1007\/s00125-011-2111-y<\/a><\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p><strong>Kortizol<\/strong> kondicion\u00e1l\u00e1sa t\u00f6rt\u00e9nt egy k\u00fcl\u00f6nleges \u00edzzel, h\u00e1rom napon \u00e1t. Az el\u0151h\u00edv\u00e1si f\u00e1zis is h\u00e1rom napon \u00e1t tartott, de sajnos itt <strong>nem tudt\u00e1k kimutatni, hogy a placebo kortizol hat\u00e1st tudott volna kifejteni<\/strong><\/p>\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0306453020305047?via%3Dihub\">Judith Tekampe, Henri\u00ebt van Middendorp, Nienke R. Biermasz, Fred C.G.J. Sweep, Onno C. Meijer, Iris C.M. Pelsma, Alberto M. Pereira, Ad R.M.M. Hermus, Andrea W.M. Evers,<\/a><br \/>Conditioning cortisol in healthy young women \u2013 A randomized controlled trial, Psychoneuroendocrinology, Volume 124, 2021, 105081, ISSN 0306-4530, https:\/\/doi.org\/10.1016\/j.psyneuen.2020.105081.<\/p><\/div>\n\n                    <\/div>\n      <\/div>\n    <\/div>\n      <div class=\"bde-faq__item\">\n      <h3 class=\"bde-faq__title-tag\">\n       <button id=\"bde-faq-134-button-7\" aria-expanded=\"false\" aria-controls=\"bde-faq-134-7\" class=\"bde-faq__question js-faq-item\">\n          <span class=\"bde-faq__title\">Pszichi\u00e1tria (ADHD, alv\u00e1szavar)<\/span>\n                           <div aria-hidden=\"true\" class=\"bde-faq__icon bde-faq__icon--inactive\">\n                                <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 32 32\">\r\n<path d=\"M31 12h-11v-11c0-0.552-0.448-1-1-1h-6c-0.552 0-1 0.448-1 1v11h-11c-0.552 0-1 0.448-1 1v6c0 0.552 0.448 1 1 1h11v11c0 0.552 0.448 1 1 1h6c0.552 0 1-0.448 1-1v-11h11c0.552 0 1-0.448 1-1v-6c0-0.552-0.448-1-1-1z\"\/>\r\n<\/svg>\n                            <\/div>\n         \t  <div aria-hidden=\"true\" class=\"bde-faq__icon bde-faq__icon--active\">\n                                <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\"><!-- Font Awesome Free 5.15.1 by @fontawesome - https:\/\/fontawesome.com License - https:\/\/fontawesome.com\/license\/free (Icons: CC BY 4.0, Fonts: SIL OFL 1.1, Code: MIT License) --><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"\/><\/svg>\n                            <\/div>\n                  <\/button>\n      <\/h3>\n      <div role=\"region\" aria-labelledby=\"bde-faq-134-button-7\" id=\"bde-faq-134-7\" class=\"bde-faq__answer\">\n        <div class=\"bde-faq__answer-content\">\n            <div class=\"breakdance-rich-text-styles\"><p><strong>ADHD-s gyerekek<\/strong> gy\u00f3gyszermennyis\u00e9g\u00e9t COLP m\u00f3dszerrel a fel\u00e9re cs\u00f6kkentve a mell\u00e9khat\u00e1sok is enyh\u00fcltek a megfelel\u0151 gy\u00f3gyszerhat\u00e1s mellett.\u00a0\u00a0<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20495473\/\">Sandler AD, Glesne CE, Bodfish JW. Conditioned placebo dose reduction: a new treatment in attention-deficit hyperactivity disorder? J Dev Behav Pediatr. 2010 Jun;31(5):369-75. doi: 10.1097\/DBP.0b013e3181e121ed. PMID: 20495473; PMCID: PMC2902360.<\/a><\/p>\n<p>Hasonl\u00f3 kis\u00e9rlet, <strong>26 ADHD-s gyermek<\/strong> r\u00e9szv\u00e9tel\u00e9vel, 7-15 \u00e9ves koroszt\u00e1lyb\u00f3l. Szint\u00e9n fel\u00e9re cs\u00f6kkentett d\u00f3zis mellett adt\u00e1k a kor\u00e1bban kondicion\u00e1lt placeb\u00f3t. Placebo n\u00e9lk\u00fcl a t\u00fcnetek romlottak, placeboval viszont szignifik\u00e1ns eredm\u00e9nyeket tudtak kimutatni. A sz\u00fcl\u0151k \u00e9s gyermekek tiszt\u00e1ban voltak a vizsg\u00e1lat menet\u00e9vel, a tan\u00e1rok azonban, akik az \u00e9rt\u00e9kel\u00e9s egy r\u00e9sz\u00e9t adt\u00e1k, nem tudt\u00e1k, hogy ki kapott placebot \u00e9s ki nem. (egyszeres vak vizsg\u00e1lat)<\/p>\n<p><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-2214.2007.00797.x\">Sandler, A.D. and Bodfish, J.W. (2008), Open-label use of placebos in the treatment of ADHD: a pilot study. Child: Care, Health and Development, 34: 104-110. https:\/\/doi.org\/10.1111\/j.1365-2214.2007.00797.x<\/a><\/p>\n<p>\u00a0<\/p>\n<p>ADHD-s gyerekek \u00e9s sz\u00fcleik v\u00e9lem\u00e9nye a kondicion\u00e1lt placebo seg\u00edts\u00e9g\u00e9vel cs\u00f6kkentett gy\u00f3gyszeradagos ter\u00e1pi\u00e1r\u00f3l. Nem statisztikai, hanem qualitativ \u00f6sszegz\u00e9s - a r\u00e9sztvev\u0151k v\u00e9lem\u00e9nyeit is olvashatjuk.<\/p>\n<p><a href=\"http:\/\/pubmed.ncbi.nlm.nih.gov\/18171452\/\">Sandler A, Glesne C, Geller G. Children's and parents' perspectives on open-label use of placebos in the treatment of ADHD. Child Care Health Dev. 2008 Jan;34(1):111-20. doi: 10.1111\/j.1365-2214.2007.00743.x. PMID: 18171452.<\/a><\/p>\n<p>\u00a0<\/p>\n<p><strong>Zolpidem tartalm\u00fa altat\u00f3<\/strong>t \u00e9s hat\u00f3anyag n\u00e9lk\u00fcli tablett\u00e1t p\u00e1ros\u00edtottak.\u00a0 B\u00e1r nem olyan hat\u00e1sos mint a folyamatos gy\u00f3gyszer a cs\u00f6kkentett adag melletti placebo is eredm\u00e9nyes.<\/p>\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1389945721004408?via%3Dihub\">Michael L. Perlis, Knashawn H. Morales, Ivan Vargas, Alexandria Muench, Mark Seewald, Nalaka Gooneratne, Michael A. Grandner, Michael E. Thase, Ted J. Kaptchuk, Robert Ader,<\/a><br \/><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1389945721004408?via%3Dihub\">Durability of treatment response to zolpidem using a partial reinforcement regimen: does this strategy require priming?,<\/a><br \/><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1389945721004408?via%3Dihub\">Sleep Medicine, Volume 87, 2021, Pages 56-61, ISSN 1389-9457, https:\/\/doi.org\/10.1016\/j.sleep.2021.04.041.<\/a><\/p>\n<p>\u00a0<\/p>\n<p>Szint\u00e9n<strong> Zolpidem<\/strong> altat\u00f3. Kevesebb aktiv gy\u00f3gyszer is el\u00e9g a hat\u00e1shoz.<\/p>\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1389945715008345?via%3Dihub\">Michael Perlis, Michael Grandner, Jarcy Zee, Erin Bremer, Julia Whinnery, Holly Barilla, Priscilla Andalia, Phil Gehrman, Knashawn Morales, Michael Thase, Richard Bootzin, Robert Ader,<\/a><br \/><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1389945715008345?via%3Dihub\">Durability of treatment response to zolpidem with three different maintenance regimens: a preliminary study,<\/a><br \/><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1389945715008345?via%3Dihub\">Sleep Medicine, Volume 16, Issue 9, 2015, Pages 1160-1168, ISSN 1389-9457, https:\/\/doi.org\/10.1016\/j.sleep.2015.06.015.<\/a><\/p><\/div>\n\n                    <\/div>\n      <\/div>\n    <\/div>\n      <div class=\"bde-faq__item\">\n      <h3 class=\"bde-faq__title-tag\">\n       <button id=\"bde-faq-134-button-8\" aria-expanded=\"false\" aria-controls=\"bde-faq-134-8\" class=\"bde-faq__question js-faq-item\">\n          <span class=\"bde-faq__title\">Autoimmun betegs\u00e9g<\/span>\n                           <div aria-hidden=\"true\" class=\"bde-faq__icon bde-faq__icon--inactive\">\n                                <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 32 32\">\r\n<path d=\"M31 12h-11v-11c0-0.552-0.448-1-1-1h-6c-0.552 0-1 0.448-1 1v11h-11c-0.552 0-1 0.448-1 1v6c0 0.552 0.448 1 1 1h11v11c0 0.552 0.448 1 1 1h6c0.552 0 1-0.448 1-1v-11h11c0.552 0 1-0.448 1-1v-6c0-0.552-0.448-1-1-1z\"\/>\r\n<\/svg>\n                            <\/div>\n         \t  <div aria-hidden=\"true\" class=\"bde-faq__icon bde-faq__icon--active\">\n                                <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\"><!-- Font Awesome Free 5.15.1 by @fontawesome - https:\/\/fontawesome.com License - https:\/\/fontawesome.com\/license\/free (Icons: CC BY 4.0, Fonts: SIL OFL 1.1, Code: MIT License) --><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"\/><\/svg>\n                            <\/div>\n                  <\/button>\n      <\/h3>\n      <div role=\"region\" aria-labelledby=\"bde-faq-134-button-8\" id=\"bde-faq-134-8\" class=\"bde-faq__answer\">\n        <div class=\"bde-faq__answer-content\">\n            <div class=\"breakdance-rich-text-styles\"><p><strong>Reumatiod Arthritisben<\/strong> pr\u00f3b\u00e1lkoztak gy\u00f3gyszer kondicion\u00e1l\u00e1ssal. Nem volt jelent\u0151s k\u00fcl\u00f6nbs\u00e9g a teljes adagot kapott p\u00e1ciensek \u00e9s a kondicion\u00e1lt p\u00e1ciensek betegs\u00e9g\u00e9nek fell\u00e1ngol\u00e1sa \u00e9s TNF-alfa szintjei k\u00f6z\u00f6tt, de a placebo csoport kicsit jobban teljes\u00edtett.\u00a0<\/p>\n<p><a href=\"https:\/\/www.mdpi.com\/1424-8247\/17\/1\/110\">Mana\u00ef, M.; van Middendorp, H.; van der Pol, J.A.; Allaart, C.F.; Dusseldorp, E.; Veldhuijzen, D.S.; Huizinga, T.W.J.; Evers, A.W.M. Can Pharmacological Conditioning as an Add-On Treatment Optimize Standard Pharmacological Treatment in Patients with Recent-Onset Rheumatoid Arthritis? A Proof-of-Principle Randomized Clinical Trial. <em>Pharmaceuticals<\/em> <b>2024<\/b>, <em>17<\/em>, 110. https:\/\/doi.org\/10.3390\/ph17010110<\/a><\/p>\n<p>\u00a0<\/p>\n<p>Ez m\u00e9g ugyan csak <strong>terv a kutat\u00e1sra, de Juvenilis Idopathias Arthritisben<\/strong> is szeretn\u00e9nek Methotrexat d\u00f3ziscs\u00f6kkent\u00e9st el\u00e9rni a gy\u00f3gyszer kondicion\u00e1l\u00e1s\u00e1val.<\/p>\n<p><a href=\"https:\/\/link.springer.com\/article\/10.1186\/s12969-020-0407-5\">Smits, R.M., Veldhuijzen, D.S., van Middendorp, H.\u00a0<i>et al.<\/i>\u00a0Pharmacological conditioning for juvenile idiopathic arthritis: a potential solution to reduce methotrexate intolerance.\u00a0<i>Pediatr Rheumatol\u00a0<\/i><b>18<\/b>, 12 (2020). https:\/\/doi.org\/10.1186\/s12969-020-0407-5<\/a><\/p>\n<p>\u00a0<\/p>\n<p><strong>Psoriasisban a kortikoszteroid<\/strong> gy\u00f3gyszer adagj\u00e1t fel\u00e9re, negyed\u00e9re v\u00e9ve is hat\u00e1sos kezel\u00e9st \u00e9rtek el a kondicion\u00e1lt placebo m\u00f3dszerrel.<\/p>\n<div class=\"citation-text margin-bottom-2\"><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC2850283\/\">Ader R, Mercurio MG, Walton J, James D, Davis M, Ojha V, Kimball AB, Fiorentino D. Conditioned pharmacotherapeutic effects: a preliminary study. Psychosom Med. 2010 Feb;72(2):192-7. doi: 10.1097\/PSY.0b013e3181cbd38b. Epub 2009 Dec 22. PMID: 20028830; PMCID: PMC2850283.<\/a><\/div>\n<div>\u00a0<\/div>\n<p><strong>Multiple Sclerosis<\/strong>ban szenved\u0151 betegek <strong>cyclophosphamid<\/strong> gy\u00f3gyszer\u00e9t kondicion\u00e1lt\u00e1k. 10-b\u0151l nyolc betegn\u00e9l leukocita sz\u00e1m cs\u00f6kken\u00e9st m\u00e9rtek a placebo alkalmaz\u00e1sakor is.<\/p>\n<div>\n<p><a href=\"https:\/\/psychiatryonline.org\/doi\/abs\/10.1176\/jnp.8.2.194\">Conditioning of cyclophosphamide-induced leukopenia in humans, The Journal of Neuropsychiatry and Clinical Neurosciences volume = 8, number = 2, pages = 194-201, 1996, doi = 10.1176\/jnp.8.2.194<\/a><\/p>\n<\/div><\/div>\n\n                    <\/div>\n      <\/div>\n    <\/div>\n      <div class=\"bde-faq__item\">\n      <h3 class=\"bde-faq__title-tag\">\n       <button id=\"bde-faq-134-button-9\" aria-expanded=\"false\" aria-controls=\"bde-faq-134-9\" class=\"bde-faq__question js-faq-item\">\n          <span class=\"bde-faq__title\">Hossz\u00fat\u00e1v\u00fa hat\u00e1s<\/span>\n                           <div aria-hidden=\"true\" class=\"bde-faq__icon bde-faq__icon--inactive\">\n                                <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 32 32\">\r\n<path d=\"M31 12h-11v-11c0-0.552-0.448-1-1-1h-6c-0.552 0-1 0.448-1 1v11h-11c-0.552 0-1 0.448-1 1v6c0 0.552 0.448 1 1 1h11v11c0 0.552 0.448 1 1 1h6c0.552 0 1-0.448 1-1v-11h11c0.552 0 1-0.448 1-1v-6c0-0.552-0.448-1-1-1z\"\/>\r\n<\/svg>\n                            <\/div>\n         \t  <div aria-hidden=\"true\" class=\"bde-faq__icon bde-faq__icon--active\">\n                                <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\"><!-- Font Awesome Free 5.15.1 by @fontawesome - https:\/\/fontawesome.com License - https:\/\/fontawesome.com\/license\/free (Icons: CC BY 4.0, Fonts: SIL OFL 1.1, Code: MIT License) --><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"\/><\/svg>\n                            <\/div>\n                  <\/button>\n      <\/h3>\n      <div role=\"region\" aria-labelledby=\"bde-faq-134-button-9\" id=\"bde-faq-134-9\" class=\"bde-faq__answer\">\n        <div class=\"bde-faq__answer-content\">\n            <div class=\"breakdance-rich-text-styles\"><p>Az al\u00e1bb k\u00e9t kutat\u00e1s nyilt placebot (OLP) nem pedig kondicion\u00e1lt nyilt placebo-t (COLP) alkalmazott. Ennek ellen\u00e9re hasznos tudni, hogy a placebo hat\u00e1s ak\u00e1r \u00e9vekig is fenn\u00e1lhat.<\/p>\n<p>\u00a0<\/p>\n<p><strong>Egy h\u00e1rom hetes OLP ter\u00e1pia hossz\u00fat\u00e1v\u00fa hat\u00e1s\u00e1t vizsg\u00e1lt\u00e1k \u2013 3 \u00e9v ut\u00e1n<\/strong> m\u00e9g mindig alacsonyabb a meg\u00e9lt f\u00e1jdalom, mint a OLP n\u00e9lk\u00fcl kezelt p\u00e1ciensek eset\u00e9ben.\u2028 <a href=\"\\&quot;https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC9916047\/\\&quot;\" target=\"\\&quot;_blank\\&quot;\" rel=\"\\&quot;noopener\\&quot;\">Kleine-Borgmann J, Dietz TN, Schmidt K, Bingel U. No long-term effects after a 3-week open-label placebo treatment for chronic low back pain: a 3-year follow-up of a randomized controlled trial. Pain. 2023 Mar 1;164(3):645-652. doi: 10.1097\/j.pain.0000000000002752. Epub 2022 Aug 10. PMID: 35947884; PMCID: PMC9916047<\/a>.<\/p>\n<p><strong>\u00d6t \u00e9ves nyomonk\u00f6vet\u00e9s<\/strong>: a ter\u00e1pia befejez\u00e9se ut\u00e1n is tov\u00e1bbi jelent\u0151s cs\u00f6kken\u00e9s volt a OLP csoportban f\u00e1jdalomcsillap\u00edt\u00f3 haszn\u00e1lat\u00e1ban(87% r\u00f3l 38%-ra), f\u00e1jdalom csillap\u00edt\u00f3t is tartalmaz\u00f3 gy\u00f3gyszerek (80%-r\u00f3l 31%-ra), antidepressz\u00e1nsok (24%-r\u00f3l 11%-ra), \u00e9s benzodiazepinek (15%-r\u00f3l 5%-ra). A kontroll csoport f\u00e1jdalomcsillap\u00edt\u00f3 ig\u00e9nye ez id\u0151 alatt emelkedett (18%-r\u00f3l 29%-ra).\u2028 <a href=\"\\&quot;https:\/\/journals.lww.com\/pain\/abstract\/2021\/05000\/open_label_placebo_for_chronic_low_back_pain__a.23.aspx\\&quot;\" target=\"\\&quot;_blank\\&quot;\" rel=\"\\&quot;noopener\\&quot;\">Carvalho, Claudiaa,*; Pais, Mariab; Cunha, Lidiac; Rebouta, Paulac; Kaptchuk, Ted J.d; Kirsch, Irvingd. Open-label placebo for chronic low back pain: a 5-year follow-up. PAIN 162(5):p 1521-1527, May 2021. | DOI: 10.1097\/j.pain.0000000000002162<\/a><\/p>\n<p>\u00a0<\/p><\/div>\n\n                    <\/div>\n      <\/div>\n    <\/div>\n      <div class=\"bde-faq__item\">\n      <h3 class=\"bde-faq__title-tag\">\n       <button id=\"bde-faq-134-button-10\" aria-expanded=\"false\" aria-controls=\"bde-faq-134-10\" class=\"bde-faq__question js-faq-item\">\n          <span class=\"bde-faq__title\">Egy\u00e9b<\/span>\n                           <div aria-hidden=\"true\" class=\"bde-faq__icon bde-faq__icon--inactive\">\n                                <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 32 32\">\r\n<path d=\"M31 12h-11v-11c0-0.552-0.448-1-1-1h-6c-0.552 0-1 0.448-1 1v11h-11c-0.552 0-1 0.448-1 1v6c0 0.552 0.448 1 1 1h11v11c0 0.552 0.448 1 1 1h6c0.552 0 1-0.448 1-1v-11h11c0.552 0 1-0.448 1-1v-6c0-0.552-0.448-1-1-1z\"\/>\r\n<\/svg>\n                            <\/div>\n         \t  <div aria-hidden=\"true\" class=\"bde-faq__icon bde-faq__icon--active\">\n                                <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 448 512\"><!-- Font Awesome Free 5.15.1 by @fontawesome - https:\/\/fontawesome.com License - https:\/\/fontawesome.com\/license\/free (Icons: CC BY 4.0, Fonts: SIL OFL 1.1, Code: MIT License) --><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"\/><\/svg>\n                            <\/div>\n                  <\/button>\n      <\/h3>\n      <div role=\"region\" aria-labelledby=\"bde-faq-134-button-10\" id=\"bde-faq-134-10\" class=\"bde-faq__answer\">\n        <div class=\"bde-faq__answer-content\">\n            <div class=\"breakdance-rich-text-styles\"><p><strong>M\u00e9g egy cikk a placebo \u00e9s a kondicion\u00e1l\u00e1s hat\u00e1sair\u00f3l.\u2028<\/strong> <a href=\"\\&quot;https:\/\/pubmed.ncbi.nlm.nih.gov\/15990450\/\\&quot;\" target=\"\\&quot;_blank\\&quot;\" rel=\"\\&quot;noopener\\&quot;\">Haour F. Mechanisms of the placebo effect and of conditioning. Neuroimmunomodulation. 2005;12(4):195-200. doi: 10.1159\/000085651. PMID: 15990450<\/a>.<\/p>\n<p>\u00a0<\/p>\n<p>A f\u00e1jdalomcsillap\u00edt\u00e1sos cikkekben l\u00e1ttuk, hogy az opi\u00e1tok j\u00f3l kondicion\u00e1lhat\u00f3k. \u00c9rdekes <strong>etikai k\u00e9rd\u00e9s<\/strong>, hogy a kondicion\u00e1l\u00e1s seg\u00edts\u00e9g\u00e9vel (szer n\u00e9lk\u00fcl) l\u00e9trehozott f\u00e1jdalomt\u0171r\u00e9s n\u00f6veked\u00e9se \u00e9s teljes\u00edtm\u00e9nyfokoz\u00f3 hat\u00e1s<strong> dopping<\/strong>nak min\u0151s\u00fcl-e sportversenyeken?<\/p>\n<div class=\"highwire-citation-info\">\n<div id=\"citation-node-367071--21669390441\" class=\"highwire-article-citation highwire-citation-type-highwire-article cite-tool-node367071\" data-node-nid=\"367071\" data-pisa=\"jneuro;27\/44\/11934\" data-pisa-master=\"jneuro;27\/44\/11934\" data-apath=\"\/jneuro\/27\/44\/11934.atom\">\n<div class=\"highwire-cite highwire-cite-highwire-article highwire-citation-jnl-eneuro-styles-jcore-standard-plus clearfix\">\n<div class=\"highwire-cite-title\"><a href=\"https:\/\/www.jneurosci.org\/content\/27\/44\/11934\">Opioid-Mediated Placebo Responses Boost Pain Endurance and Physical Performance: Is It Doping in Sport Competitions?<\/a><\/div>\n<div class=\"highwire-cite-authors\"><a href=\"https:\/\/www.jneurosci.org\/content\/27\/44\/11934\"><span class=\"highwire-citation-authors\"><span class=\"highwire-citation-author first\" data-delta=\"0\">Fabrizio Benedetti<\/span>, <span class=\"highwire-citation-author\" data-delta=\"1\">Antonella Pollo<\/span>, <span class=\"highwire-citation-author\" data-delta=\"2\">Luana Colloca<\/span><\/span><\/a><\/div>\n<div class=\"highwire-cite-metadata\"><a href=\"https:\/\/www.jneurosci.org\/content\/27\/44\/11934\"><span class=\"highwire-cite-metadata-journal highwire-cite-metadata\">Journal of Neuroscience <\/span><span class=\"highwire-cite-metadata-date highwire-cite-metadata\">31 October 2007, <\/span><span class=\"highwire-cite-metadata-volume highwire-cite-metadata\">27 <\/span><span class=\"highwire-cite-metadata-issue highwire-cite-metadata\">(44) <\/span><span class=\"highwire-cite-metadata-pages highwire-cite-metadata\">11934-11939; <\/span><\/a><span class=\"highwire-cite-metadata-doi highwire-cite-metadata\"><span class=\"label\">DOI:<\/span> 10.1523\/JNEUROSCI.3330-07.2007 <\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n<div>\u00a0<\/div>\n<div><strong>Interferon (beta)-1a injekciot<\/strong> adtak egy specialis \u00edz\u0171 folyad\u00e9kkal, de csak egyetlen alkalommal. Nyolc nappal k\u00e9s\u0151bb fiziol\u00f3gi\u00e1s s\u00f3oldatot kaptak az alanyok injekcioban, ugyanazzal az itallal egy\u00fctt. Az egyszeri alkalommal val\u00f3 tanul\u00e1si folyamat nem hozott semmilyen eredm\u00e9nyt.<\/div>\n<div>\n<div class=\"citation-text\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15885259\/\">Goebel MU, H\u00fcbell D, Kou W, Janssen OE, Katsarava Z, Limmroth V, Schedlowski M. Behavioral conditioning with interferon beta-1a in humans. Physiol Behav. 2005 Apr 13;84(5):807-14. doi: 10.1016\/j.physbeh.2005.03.021. Epub 2005 Apr 26. PMID: 15885259.<\/a><\/div>\n<\/div><\/div>\n\n                    <\/div>\n      <\/div>\n    <\/div>\n  \n<\/div>\n<\/div>\n<\/div><div class=\"bde-column-266-114 bde-column\">\n  \n  \n\t\n\n\n\n<div class=\"bde-globalblock-266-133 bde-globalblock\"><div class=\"bde-div-296-100-296-1 bde-div bde-div-296-100\">\n  \n  \n\t\n\n\n\n<div class=\"bde-div-296-101-296-1 bde-div bde-div-296-101\">\n  \n  \n\t\n\n\n\n<div class=\"bde-div-296-102-296-1 bde-div bde-div-296-102\">\n  \n  \n\t\n\n\n\n<img decoding=\"async\" class=\"bde-image2-296-103-296-1 bde-image2 bde-image2-296-103\" src=\"https:\/\/doctor-to-be.org\/wp-content\/uploads\/2025\/11\/Heart-150x150.png\" loading=\"lazy\" srcset=\"https:\/\/doctor-to-be.org\/wp-content\/uploads\/2025\/11\/Heart-150x150.png 150w, https:\/\/doctor-to-be.org\/wp-content\/uploads\/2025\/11\/Heart-300x300.png 300w\" sizes=\"(max-width: 150px) 100vw, 150px\"><h4 class=\"bde-heading-296-104-296-1 bde-heading bde-heading-296-104\">\nEinen Medizinstudenten unterst\u00fctzen\n<\/h4><div class=\"bde-text-296-105-296-1 bde-text bde-text-296-105\">\nM\u00f6chtest du einen kleinen Betrag in etwas Gutes verwandeln?\nUnterst\u00fctze die Verwirklichung eines Traums und die Genesung anderer! Jeder kleine Beitrag hilft\n<\/div>\n<\/div><div class=\"bde-button-296-106-296-1 bde-button bde-button-296-106\">\n        \n    \n    \n    \n    \n            \n                    \n            \n            \n\n    \n    \n    \n    \n    \n    <a class=\"breakdance-link button-atom button-atom--secondary bde-button__button\" href=\"\/tamogatas\/\" target=\"_self\" data-type=\"url\"  >\n\n    \n        <span class=\"button-atom__text\">Ich helfe auch!<\/span>\n\n        \n        \n                <\/a>\n\n    \n\n\n<\/div>\n<\/div><div class=\"bde-div-296-107-296-1 bde-div bde-div-296-107\">\n  \n  \n\t\n\n\n\n<div class=\"bde-div-296-108-296-1 bde-div bde-div-296-108\">\n  \n  \n\t\n\n\n\n<img decoding=\"async\" class=\"bde-image2-296-109-296-1 bde-image2 bde-image2-296-109\" src=\"https:\/\/doctor-to-be.org\/wp-content\/uploads\/2025\/11\/Light-bulb-150x150.png\" loading=\"lazy\" srcset=\"https:\/\/doctor-to-be.org\/wp-content\/uploads\/2025\/11\/Light-bulb.png 624w, https:\/\/doctor-to-be.org\/wp-content\/uploads\/2025\/11\/Light-bulb-300x300.png 300w, https:\/\/doctor-to-be.org\/wp-content\/uploads\/2025\/11\/Light-bulb-150x150.png 150w\" sizes=\"(max-width: 624px) 100vw, 624px\"><h4 class=\"bde-heading-296-110-296-1 bde-heading bde-heading-296-110\">\nBrauchst du etwas Inspiration?\nMedizinstudium mit \u00fcber 40\n<\/h4><div class=\"bde-text-296-111-296-1 bde-text bde-text-296-111\">\nIn kleinen Newslettern berichte ich gelegentlich auch \u00fcber mein Medizinstudium\n<\/div>\n<\/div><div class=\"bde-button-296-112-296-1 bde-button bde-button-296-112\">\n        \n    \n    \n    \n    \n            \n                    \n            \n            \n\n    \n    \n    \n    \n    \n    <a class=\"breakdance-link button-atom button-atom--secondary bde-button__button\" href=\"\/kapcsolat\/\" target=\"_self\" data-type=\"url\"  >\n\n    \n        <span class=\"button-atom__text\">Newsletter abonnieren<\/span>\n\n        \n        \n                <\/a>\n\n    \n\n\n<\/div>\n<\/div><div class=\"bde-div-296-113-296-1 bde-div bde-div-296-113\">\n  \n  \n\t\n\n\n\n<div class=\"bde-div-296-114-296-1 bde-div bde-div-296-114\">\n  \n  \n\t\n\n\n\n<img decoding=\"async\" class=\"bde-image2-296-115-296-1 bde-image2 bde-image2-296-115\" src=\"https:\/\/doctor-to-be.org\/wp-content\/uploads\/2025\/12\/Gift-Box-with-Ribbon-150x150.png\" loading=\"lazy\" srcset=\"https:\/\/doctor-to-be.org\/wp-content\/uploads\/2025\/12\/Gift-Box-with-Ribbon.png 624w, https:\/\/doctor-to-be.org\/wp-content\/uploads\/2025\/12\/Gift-Box-with-Ribbon-300x263.png 300w\" sizes=\"(max-width: 624px) 100vw, 624px\"><h4 class=\"bde-heading-296-116-296-1 bde-heading bde-heading-296-116\">\nEin kleines Buch als Geschenk, von mir f\u00fcr dich\n<\/h4><div class=\"bde-text-296-117-296-1 bde-text bde-text-296-117\">\nW\u00e4hrend meiner 2.000 Stunden als ehrenamtlicher Rettungssanit\u00e4ter habe ich die sch\u00f6nen, spannenden, be\u00e4ngstigenden und schmerzhaften Erfahrungen, die ich gemacht habe, in Form von 50-W\u00f6rter-Geschichten niedergeschrieben.\n<\/div>\n<\/div><div class=\"bde-button-296-118-296-1 bde-button bde-button-296-118\">\n        \n    \n    \n    \n    \n            \n                    \n            \n            \n\n    \n    \n    \n    \n    \n    <a class=\"breakdance-link button-atom button-atom--secondary bde-button__button\" href=\"\/ajandek-konyv\/\" target=\"_self\" data-type=\"url\"  >\n\n    \n        <span class=\"button-atom__text\">Weiter<\/span>\n\n        \n        \n                <\/a>\n\n    \n\n\n<\/div>\n<\/div>\n<\/div><\/div>\n<\/div><\/div><\/div>\n<\/section><div class=\"bde-globalblock-266-140 bde-globalblock\"><section class=\"bde-section-298-100-298-1 bde-section bde-section-298-100\">\n  \n  \n\t\n\n\n\n<div class=\"section-container\"><div class=\"bde-button-298-101-298-1 bde-button bde-button-298-101\">\n        \n              \n    \n    \n    \n            \n                    \n            \n                           \n                       \n                 \n\n    \n    \n              \n                    \n    \n    <a class=\"breakdance-link button-atom button-atom--primary bde-button__button\" href=\"#\" target=\"_self\" data-type=\"action\"  id=\"information\" data-action='{\"type\":\"popup\",\"popupOptions\":{\"popupId\":\"81\",\"popupAction\":\"open\"}}' >\n\n    \n        <span class=\"button-atom__text\">Warnhinweis<\/span>\n\n        \n        \n                <\/a>\n\n    \n\n\n<\/div><div class=\"bde-code-block-298-102-298-1 bde-code-block bde-code-block-298-102\">\n\n\n\n<\/div><\/div>\n<\/section><\/div>","protected":false},"excerpt":{"rendered":"<p>Forschung Erhebung der Wirkungen eines konditionierten Open-Label-Placebos mit dem Ziel, eine m\u00f6gliche Reduzierung der symptomatischen medikament\u00f6sen Behandlung unter \u00e4rztlicher Begleitung zu untersuchen oder ihre Wirkung zu verst\u00e4rken. Forschung in den Bereichen Behandlung chronischer Schmerzen, symptomatische Behandlung allergischer Beschwerden, Verst\u00e4rkung der Wirkung einer Chemotherapie, Unterst\u00fctzung der Rauchentw\u00f6hnung, Koffein ersetzen, Reduzierung von Depressionen und Panikattacken sowie Unterst\u00fctzung [&hellip;]<\/p>\n","protected":false},"author":0,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_breakdance_hide_in_design_set":false,"_breakdance_tags":"","footnotes":""},"class_list":["post-266","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.7 (Yoast SEO v27.7) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Forschung - doctobe<\/title>\n<meta name=\"description\" content=\"COLP-Forschung von Gergely PAPP: Erfahrungen zu Medikamentenwirkung, Schmerz, Allergie und Lebensstilver\u00e4nderung.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/doctor-to-be.org\/de\/forschung\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Forschung\" \/>\n<meta property=\"og:description\" content=\"COLP-Forschung von Gergely PAPP: Erfahrungen zu Medikamentenwirkung, Schmerz, Allergie und Lebensstilver\u00e4nderung.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/doctor-to-be.org\/de\/forschung\/\" \/>\n<meta property=\"og:site_name\" content=\"doctobe\" \/>\n<meta property=\"article:modified_time\" content=\"2026-06-04T14:54:38+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/doctor-to-be.org\/wp-content\/uploads\/2026\/03\/20250404-PTE-AOK-Alumni-Magazin-portre-Papp-Gergely-11424347-csortos-szabolcs-.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1600\" \/>\n\t<meta property=\"og:image:height\" content=\"2400\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/doctor-to-be.org\\\/de\\\/forschung\\\/\",\"url\":\"https:\\\/\\\/doctor-to-be.org\\\/de\\\/forschung\\\/\",\"name\":\"Forschung - 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